A Study on Head and Neck Malignant Lymphoma Diagnosed by Core Needle Biopsy

DOI Web Site Web Site 4 References

Bibliographic Information

Other Title
  • コア針生検（core needle biopsy：CNB）により診断し得た頭頸部悪性リンパ腫の検討
  • 臨床 コア針生検(core needle biopsy : CNB)により診断し得た頭頸部悪性リンパ腫の検討
  • リンショウ コア ハリ セイケン(core needle biopsy : CNB)ニ ヨリ シンダン シエタ トウケイブ アクセイ リンパシュ ノ ケントウ

Search this article

Abstract

<p>Head and neck malignant lymphoma accounts for less than 10% of case of head and neck malignancies. Because patients with head and neck malignant lymphoma often present with neck swellings, they are often examined by otolaryngologists. Fine-needle aspiration cytology (FNAC) may yield useful clue to the ­diagnosis, although tissue biopsy is required for reliable diagnosis and classification of lymphoma, so that appropriate treatment can be administered. Although open biopsy of lymph nodes has been regarded as the standard method of tissue sampling, this method has drawbacks, including the risks associated with general anesthesia and surgical invasion, as well as the high cost and relatively long time to diagnosis. Core needle biopsy (CNB) provides a possible alternative to traditional FNAC and open biopsy. In this study, we assessed the usefulness of CNB in determining the histology of head and neck malignant lymphomas.</p><p>Seven patients with suspected head and neck malignant lymphoma were examined by CNB between June 2017 and November 2018. Indications for CNB included a lesion diameter of ≥1.5 cm, lesion location at a distance from important blood vessels as judged by prior imaging examination, and the absence of bleeding tendency. US-guided CNB was performed using a Bard® Monopty® 14 G×90 mm, with a stroke length of 11 mm, or a Temno Evolution® 14 G×60 mm, with a stroke length of 10/20 mm.</p><p>Of the seven lesions, four were in the neck, one was in the thyroid, and one was in the parotid gland. The mean lesion size was 4.3 cm (range, 2.5–6.8 cm). In all patients, the US-guided CNB was performed under local anesthesia. Histopathologically, four patients had diffuse large cell lymphoma, one had follicular lymphoma, one had MALT lymphoma, and one had ALK-negative anaplastic large cell lymphoma. The ­histopathological diagnosis could be made in all the patients by examination of the US-guided CNB, with none of the patients requiring further open biopsy. The shortest time from the first visit to biopsy was 0 day, with the CNB samples taken at the first outpatient consultation. None of the patients developed compli­cations such as hemorrhage, hematoma, infection, or facial nerve palsy.</p><p>Lesions suspected as being malignant lymphoma not requiring surgical excision may be diagnosed by US-guided CNB, reducing the burden of invasion on the patients.</p>

Journal

References(4)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top