Researches on nanophosphors for labeling biomolecules

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  • ISOBE Tetsuhiko
    Department of Applied Chemistry, Faculty of Science and Technology, Keio University

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  • 生体分子ラベル用ナノ蛍光体に関する研究
  • セイタイ ブンシ ラベルヨウ ナノ ケイコウタイ ニ カンスル ケンキュウ

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<p>CdSe/ZnS quantum dots with a core/shell microstructure have been widely used as fluorescent probes for detecting specific biological reactions ; thus, fluorescent nanoparticles for use as biological probes have attracted much attention. In this review the structural and optical features of quantum dots, the surface modification for conjugating biomolecules, and the toxicity of cadmium are introduced. In addition to quantum dots, recent works on rare-earth-doped nanophosphors with visible and near-infrared emission, fluorescent microbeads with nanophosphors, and nanoparticle probes for dual modal imaging of fluorescence and magnetic resonance are summarized.</p>

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  • Oyo Buturi

    Oyo Buturi 77 (12), 1415-1424, 2008-12-10

    The Japan Society of Applied Physics

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