Long-Term Incidence and Details of Bleeding Events After Everolimus-Eluting Stent Implantation ― 7–8-Year Outcomes ―
-
- Miura Katsuya
- Department of Cardiology, Kurashiki Central Hospital
-
- Shimada Takenobu
- Department of Cardiology, Kurashiki Central Hospital
-
- Ohya Masanobu
- Department of Cardiology, Kurashiki Central Hospital
-
- Murai Ryosuke
- Department of Cardiology, Kurashiki Central Hospital
-
- Amano Hidewo
- Department of Cardiology, Kurashiki Central Hospital
-
- Kubo Shunsuke
- Department of Cardiology, Kurashiki Central Hospital
-
- Tada Takeshi
- Department of Cardiology, Kurashiki Central Hospital
-
- Tanaka Hiroyuki
- Department of Cardiology, Kurashiki Central Hospital
-
- Fuku Yasushi
- Department of Cardiology, Kurashiki Central Hospital
-
- Goto Tsuyoshi
- Department of Cardiology, Kurashiki Central Hospital
-
- Kadota Kazushige
- Department of Cardiology, Kurashiki Central Hospital
この論文をさがす
抄録
<p>Background:To date, the long-term incidence and details of major bleeding (MB) and coronary thrombotic events (CTE) in patients with everolimus-eluting stent (EES) implantation have not been made clear.</p><p>Methods and Results:The study population comprised 1,193 patients treated with EES without in-hospital events between 2010 and 2011. MB was defined as the occurrence of a Bleeding Academic Research Consortium type 3 or 5 bleeding event. The mean follow-up period was 2,996±433 days. Cumulative rate of MB was 7.4% and 10.8% at 5 and 8 years, respectively. Of 46 patients with intracranial bleeding, 20 had trauma-related intracranial bleeding. Cumulative rates of definite stent thrombosis and CTE at 8 years were 0.4% and 5.9%, respectively. Multivariate analysis revealed low body mass index (<23) (hazard ratio (HR), 1.57; 95% confidence interval (CI), 1.03–2.36; P=0.03) and concomitant use of oral anticoagulants (HR, 2.17; 95% CI, 1.30–3.50; P=0.004) as independent risk factors of MB and previous PCI (HR, 2.47; 95% CI, 1.29–1.00; P=0.006) as the factor for CTE.</p><p>Conclusions:MB is not uncommon and is a long-term hazard, but the occurrence of stent thrombosis is very low after EES implantation. Approximately half of the cases involving intracranial bleeding were associated with trauma.</p>
収録刊行物
-
- Circulation Journal
-
Circulation Journal 83 (11), 2242-2249, 2019-10-25
一般社団法人 日本循環器学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390564227327237376
-
- NII論文ID
- 130007733360
-
- NII書誌ID
- AA11591968
-
- ISSN
- 13474820
- 13469843
-
- NDL書誌ID
- 030030452
-
- PubMed
- 31495801
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可