Examination of precipitation and sedimentation in quantity-restricted cold aqueous suspensions of granular Japanese herbal extracts commonly used during palliative and supportive care
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- MATSUOKA Yuriko
- Department of Anesthesiology, National Hospital Organization Osaka Toneyama Medical Center Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine
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- NAKANISHI Miho
- Department of Anesthesiology, Shiga University of Medical Science
Bibliographic Information
- Other Title
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- がんの支持療法や緩和医療における漢方薬治療―低温少量水での漢方エキス顆粒の懸濁時沈殿率について―
- ガン ノ シジ リョウホウ ヤ カンワ イリョウ ニ オケル カンポウヤク チリョウ : テイオン ショウリョウスイ デ ノ カンポウ エキス カリュウ ノ ケンダクジ チンデンリツ ニ ツイテ
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Description
<p>Purpose: To ensure controlled dosage of Japanese herbal medicines given in small quantities of water, sedimentation must be minimized. When anorexia or nausea are present, medicinal-extract suspensions in cold water are consumed more easily; finding no reports on this, we examined how sedimentation of different medications varied in icy-cold to lukewarm water. Method: Into separate 20 ml syringes, each containing 15 ml of distilled water at either 0℃, 20℃ or 40℃, we dropped half a sachet of each of 24 types of herbal extract granules. At just after and 5 min after suspension, the samples were agitated for 1 min; at 10 min after suspension, sedimentation was measured. Results: At 0℃ and 20℃, nine formulations showed no more sedimentation than at 40℃; of these, one had no macroscopic sedimentation at any sampling temperature. Conclusion: Some Japanese herbal formulations may be effectively administered in cool and cold water.</p>
Journal
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- Journal of Japan Society of Pain Clinicians
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Journal of Japan Society of Pain Clinicians 26 (4), 297-302, 2019-10-25
Japan Society of Pain Clinicians
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Details 詳細情報について
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- CRID
- 1390564227340351360
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- NII Article ID
- 130007742497
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- NII Book ID
- AN10440947
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- ISSN
- 18841791
- 13404903
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- NDL BIB ID
- 030076168
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed