The comparison of parotid gland carcinoma and submandibular gland carcinoma―Results of a multi-institutional retrospective study

  • Yamada Koichiro
    Department of Otolaryngology, Japanese Red Cross Wakayama Medical Center
  • Honda Keigo
    Department of Otolaryngology, Japanese Red Cross Wakayama Medical Center
  • Tanaka Shinzo
    Department of Otolaryngology-Head & Neck Surgery, Japanese Red Cross Osaka Hospital
  • Tamaki Hisanobu
    Department of Otolaryngology-Head & Neck Surgery, Kurashiki Central Hospital
  • Kojima Tsuyoshi
    Department of Otolaryngology, Tenri Hospital
  • Shinohara Shogo
    Department of Otolaryngology-Head & Neck Surgery, Kobe City Medical Center General Hospital
  • Takebayashi Shinji
    Department of Otolaryngology-Head & Neck Surgery, Kobe City Medical Center General Hospital
  • Maetani Toshiki
    Department of Otolaryngology-Head and Neck Surgery, Medical Research Institute, Kitano Hospital
  • Asato Ryo
    Department of Otolaryngology-Head & Neck Surgery, National Hospital Organization Kyoto Medical Center
  • Tateya Ichiro
    Department of Otolaryngology-Head & Neck Surgery, Kyoto University Graduate School of Medicine
  • Kitamura Morimasa
    Department of Otolaryngology-Head & Neck Surgery, Kyoto University Graduate School of Medicine
  • Mizuta Masanobu
    Department of Otolaryngology-Head & Neck Surgery, Kyoto University Graduate School of Medicine
  • Kitani Yoshiharu
    Department of Otorhinolaryngology-Head & Neck surgery, Shizuoka General Hospital
  • Ushiro Koji
    Department of Otolaryngology, Japanese Red Cross Otsu Hospital
  • Ichimaru Kazuyuki
    Department of Otolaryngology-Head & Neck Surgery, Kokura Memorial Hospital
  • Kumabe Yohei
    Department of Otolaryngology-Head & Neck Surgery, Hyogo Prefectural Amagasaki General Medical Center
  • Omori Koichi
    Department of Otolaryngology-Head & Neck Surgery, Kyoto University Graduate School of Medicine

Bibliographic Information

Other Title
  • 耳下腺癌と顎下腺癌の比較:多施設共同による後方視的研究

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Abstract

Objective: Parotid gland carcinoma (PGC) and submandibular gland carcinoma (SMGC) are relatively rare. The aim of this retrospective study was to compare the clinical outcomes of PGC and SMGC.<br>Patients: Our study included 260 patients (195 with PGC and 65 with SMGC) who underwent initial surgical treatment at Kyoto University and its affiliated hospitals between 2006 and 2015. <br>Results: A total of 44% of the PGCs and 58% of the SMGCs were classified as high-grade malignancies. The sensitivity of fine-needle aspiration cytology was 50% for PGC and 75% for SMGC. At a mean follow-up time of 3.6 years, the 3-year overall survival, disease-specific survival (DSS), locoregional control, and no distant metastasis (NDM) rates for PGC were 85%, 89%, 85%, and 87%, respectively, while those for SMGC were 74%, 74%, 90%, and 65%, respectively. Furthermore, the DSS and NDM rates for SMGC were statistically significantly lower than those for PGC. <br>Conclusions: In comparison to PGC, SMGC has a higher risk of distant metastasis and a poorer DSS rate.

Journal

  • Toukeibu Gan

    Toukeibu Gan 44 (1), 39-45, 2018

    Japan Society for Head and Neck Cancer

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