Force Spectrometry for Needle Insertion to a Living Cell(Current Topic)

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  • 細胞への針挿入の力学挙動(最近の研究から)
  • 最近の研究から 細胞への針挿入の力学挙動
  • サイキン ノ ケンキュウ カラ サイボウ エ ノ ハリ ソウニュウ ノ リキガク キョドウ

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Abstract

Atomic force microscopy (AFM) enables not only nano scale imaging but also a force spectrometric analysis for molecular structure or inter (intra) molecular interactions. We have developed a technology for manipulating living cells using an ultrathin needle (nanoneedle) controlled by AFM system without damage to the cell. The force curve observation informs us whether needle can be penetrated into cell or not. Here we present basic findings about the most suitable diameter and shape of nanoneedle.

Journal

  • Butsuri

    Butsuri 61 (5), 356-360, 2006-05-05

    The Physical Society of Japan

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