Report of Breas t and Thyroi d Cancer Prone Fami l i es

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  • Ito Kohei
    Department of Surgery, Hoshi General Hospital The Second Department of Surgery, School of Medicine, Fukushima Medical University
  • Nomizu Tadashi
    Department of Surgery, Hoshi General Hospital The Second Department of Surgery, School of Medicine, Fukushima Medical University Tohoku Familial Tumor Association
  • Yamada Mutsuo
    Department of Surgery, Hoshi General Hospital
  • Katagata Naoto
    Department of Surgery, Hoshi General Hospital
  • Watanabe Fumiaki
    Department of Surgery, Hoshi General Hospital
  • Yamaki Yoshio
    Department of Surgery, Hoshi General Hospital
  • Fukushima Toshihiko
    The Second Department of Surgery, School of Medicine, Fukushima Medical University
  • Suzuki Shinichi
    The Second Department of Surgery, School of Medicine, Fukushima Medical University
  • Tsuchiya Atsuo
    The Second Department of Surgery, School of Medicine, Fukushima Medical University
  • Takenoshita Seiichi
    The Second Department of Surgery, School of Medicine, Fukushima Medical University
  • Abe Rikiya
    Tohoku Familial Tumor Association

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Other Title
  • 乳癌–甲状腺癌家系

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Thyroid cancer is often found in tumor spectra of familial breast cancer and occur frequently in primary multiple canceres including breast cancer. We herein report five breast-thyroid cancer prone families. Genetic testing was performed in only one family, then genetic relation to thyroid cancer was obscure. According to our clinical observation, there are two types of breast-thyroid cancer prone families: 1) thyroid cancer occurring in BRCA linked hereditary breast cancer families, and 2) thyroid and breast cancer were clustered in families. Taking a family history in clinical practice is important to reveal cancer prone families.

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