A Case of Necrobiotic Xanthogranuloma as Initially Diagnosed to Be Cutaneous Sarcoidosis

DOI

Bibliographic Information

Other Title
  • 初発病変が皮膚サルコイド様であった Necrobiotic Xanthogranuloma の1例

Abstract

An 80-year-old Japanese man consulted our hospital for dark reddish papules and plaques on the extremities. Based on the histopathological finding of naked granulomas in the dermis, we diagnosed the eruption as cutaneous sarcoidosis. During the 18-month application of topical corticosteroids, the eruption deteriorated to ulceration. We performed a secondary skin biopsy. Many Touton-type giant cells with necrobiosis were noted in the dermis, and we diagnosed him with necrobiotic xanthogranuloma (NXG). In addition, we found monoclonal gammopathy. His skin lesion was improved by oral prednisolone. We speculate the pathogenesis of NXG to be due to the involvement of macrophages, similar with cutaneous sarcoidosis.Skin Research, 17: 70-74, 2018

Journal

  • Hifu no kagaku

    Hifu no kagaku 17 (2), 70-74, 2018

    Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association

Keywords

Details 詳細情報について

  • CRID
    1390564238054103424
  • NII Article ID
    130007530776
  • DOI
    10.11340/skinresearch.17.2_70
  • ISSN
    18839614
    13471813
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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