Anal Canal Cancer with Pagetoid Spread without a Macroscopic Finding—A Case Report—

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  • 肉眼的に明らかな所見を認めなかった肛門管癌pagetoid spreadの1例
  • 症例 肉眼的に明らかな所見を認めなかった肛門管癌pagetoid spreadの1例
  • ショウレイ ニクガンテキ ニ アキラカ ナ ショケン オ ミトメナカッタ コウモンカンガン pagetoid spread ノ 1レイ

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A 66-year-old woman was admitted to our hospital with complaints of bloody stools. Endoscopic examination revealed a type 1 tumor in the lower rectum. We performed laparoscopic abdominoperineal resection and classified the tumor as cStage I (T2N0M0). Macroscopic findings of the resected specimen showed a type 1 tumor with no abnormal findings in the surrounding mucosa and skin. Pathological examination revealed Paget cell infiltration of the epidermis surrounding the tumor. Immunostaining was performed, and a diagnosis of anal canal adenocarcinoma with Pagetoid spread (PS) was made. The maximum diameter of the PS was 102 mm, and pathological staging was classified as pStage I (pT2pN0M0). An accurate diagnosis of lesion spread is important for anal canal cancer with PS, but in this case, preoperative evaluation was difficult because of a lack of macroscopic abnormal findings. We report this rare case because we consider it noteworthy.

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