Commentary on Japanese Pediatric Guideline for the Treatment and Management of Asthma 2017 Chapter 5 Objective evaluation of asthma : lung function and biomarkers

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  • 第5章 病態評価のための検査法

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Abstract

<p> Objective evaluation is important in diagnosis and treatment of asthma. In the previous version of the Japanese Pediatric Asthma Guideline (JPGL), lung function tests were mainly covered. In the new JPGL2017, the chapter has been comprehensively updated to cover broader area including markers for Th2-deviated immune reactions (IgE, allergen specific IgE, blood eosinophil count and skin prick test), lung function, bronchial hyperresponsiveness and airway inflammation (exhaled nitric oxide and sputum test). Emerging biomarkers such as forced oscillation technique and periostin are also described. Blood gas and SpO2 tests have been moved to the chapter of management of acute exacerbation.</p><p> Spirometry is the most important test in evaluation of asthma and is explained in detail with special emphasis on testing methods for young children.</p>

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