Degenerative Myelopathy in a Shetland Sheepdog
-
- GODA Mai
- MIYA ANIMAL HOSPITAL
-
- MIYA Yutaka
- MIYA ANIMAL HOSPITAL
-
- MIE Keiichiro
- Graduate School of Life and Environmental Sciences, Osaka Prefecture University
-
- CHAMBERS James
- Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, Tokyo University
-
- UCHIDA Kazuyuki
- Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, Tokyo University
-
- AKIYOSHI Hideo
- Graduate School of Life and Environmental Sciences, Osaka Prefecture University
Bibliographic Information
- Other Title
-
- 変性性脊髄症と診断したシェットランド・シープドッグの1例
- 変性性脊髄症と診断したシェットランド・シープドックの1例
- ヘンセイセイ セキズイショウ ト シンダン シタ シェットランド ・ シープドック ノ 1レイ
Search this article
Description
<p>A spayed, female Shetland sheepdog diagnosed with Hansen type II intervertebral disc disease showed progressive ataxia and loss of bark. Superoxide dismutase (SOD) 1 mutation analysis confirmed homozygous mutation. The dog died from insufficient breathing on day 859, necropsy was carried out, and histology of the brain and spinal cord was examined. Histopathological examinations revealed myelin loss, axonal degeneration, and diffuse proliferation of astrocytes in the spinal white matter, as well as neuronal loss and chromatolysis of remaining neuronal cells in the ventral horn. These lesions almost conform to those of canine degenerative myelopathy (DM). For Shetland sheepdogs with homozygous SOD1 mutation and symptoms of progressive ataxia, canine DM should be considered as a possible differential diagnosis.</p>
Journal
-
- Journal of the Japan Veterinary Medical Association
-
Journal of the Japan Veterinary Medical Association 72 (1), 43-47, 2019-01-20
Japan Veterinary Medical Association
- Tweet
Details 詳細情報について
-
- CRID
- 1390564238077324160
-
- NII Article ID
- 130007602189
-
- NII Book ID
- AN00191857
-
- ISSN
- 21860211
- 04466454
-
- NDL BIB ID
- 029419894
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed