Current Key Issues in Transcatheter Aortic Valve Replacement Undergoing a Paradigm Shift
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- Hwang In-Chang
- Division of Cardiology, Department of Internal Medicine, Seoul National University Bundang Hospital Cardiovascular Center, Department of Internal Medicine, Seoul National University Hospital
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- Hayashida Kentaro
- Department of Cardiology, Keio University School of Medicine
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- Kim Hyo-Soo
- Cardiovascular Center, Department of Internal Medicine, Seoul National University Hospital
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<p>As a new technology in the management of valvular heart disease, transcatheter aortic valve replacement (TAVR) has drawn much attention since its emergence. To date, numerous studies have investigated the safety and efficacy of TAVR in patients of various risk profiles with severe aortic stenosis (AS) and demonstrated comparable or superior outcomes of TAVR when compared with surgical aortic valve replacement (SAVR). The favorable outcomes of TAVR in inoperable patients, as well as in high- and intermediate-risk patients, are endorsed in current guidelines, and trials of low-risk patients have shown non-inferior or even superior results of TAVR than for SAVR, suggesting that the clinical indications of TAVR can be expanded to low-risk patients. Moreover, a therapeutic role of TAVR has been suggested in various aortic valve (AV) diseases, such as bicuspid AV, moderate AS with heart failure, aortic regurgitation, and bioprosthetic valve failure. In this review, we summarize the current issues of TAVR in various patient populations and discuss the expanding clinical indications of TAVR, which are driving a major paradigm shift in the management of AV disease.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 83 (5), 952-962, 2019-04-25
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390564238086998656
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- NII論文ID
- 130007636988
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 029661250
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- PubMed
- 30956265
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- 本文言語コード
- en
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- データソース種別
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- NDL
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