Massive Biventricular Myocardial Calcification in a Patient with Fulminant Myocarditis Requiring Ventricular Assist Device Support

  • Kimura Yuki
    Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Japan
  • Seguchi Osamu
    Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Japan
  • K. Kono Atsushi
    Department of Radiology, National Cerebral and Cardiovascular Center, Japan
  • Matsumoto Manabu
    Department of Pathology, National Cerebral and Cardiovascular Center, Japan
  • Kumai Yuto
    Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Japan
  • Kuroda Kensuke
    Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Japan
  • Nakajima Seiko
    Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Japan
  • Watanabe Takuya
    Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Japan
  • Matsumoto Yorihiko
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center, Japan
  • Fukushima Satsuki
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center, Japan
  • Yanase Masanobu
    Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Japan
  • Fujita Tomoyuki
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center, Japan
  • Ishibashi-Ueda Hatsue
    Department of Pathology, National Cerebral and Cardiovascular Center, Japan
  • Kobayashi Junjiro
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center, Japan
  • Fukushima Norihide
    Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Japan

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Description

<p>The natural course of myocardial calcification is unclear. We herein report a case of massive biventricular myocardial calcification associated with fulminant myocarditis and present its natural course. The patient was a 15-year-old boy. Massive calcification was detected in both ventricles on computed tomography several months after left ventricular assist device placement. Although the calcification gradually regressed, the patient's cardiac function did not recover, and he underwent heart transplantation after a waiting period of 3 years. A histological examination revealed severe fibrosis in both ventricles of the original heart. Myocardial calcification might suggest severe myocardial inflammation and injury in cases of fulminant myocarditis. </p>

Journal

  • Internal Medicine

    Internal Medicine 58 (9), 1283-1286, 2019-05-01

    The Japanese Society of Internal Medicine

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