Total Synthesis of 3-<i>epi</i>-Juruenolide C

DOI Web Site Web Site PubMed 42 References Open Access
  • Kutsumura Noriki
    International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba Department of Chemistry, Faculty of Science, Tokyo University of Science
  • Inagaki Mai
    Department of Chemistry, Faculty of Science, Tokyo University of Science
  • Kiriseko Akito
    Department of Chemistry, Faculty of Science, Tokyo University of Science
  • Saito Takao
    Department of Chemistry, Faculty of Science, Tokyo University of Science

Bibliographic Information

Other Title
  • Highlighted Paper selected by Editor-in-Chief : Total Synthesis of 3-epi-Juruenolide C

Search this article

Description

<p>In this study, the total synthesis of 3-epi-juruenolide C is achieved in 10 steps (longest linear sequence) starting from ethyl (2E,4S,5S)-4,5-dihydroxy-2-hexenoate. The synthetic highlights of our approach include one-pot regioselective bromination, intramolecular carbonylation using bis(triphenylphosphine)dicarbonylnickel, and face-selective hydrogenation using a homogeneous Wilkinson’s catalyst.</p>

Journal

References(42)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top