ヒトの寒冷適応とUCP1 遺伝子多型との関連

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タイトル別名
  • THE RELATIONSHIP BETWEEN HUMAN COLD ADAPTATION AND UCP1 GENOTYPE.
  • ヒト ノ カンレイ テキオウ ト UCP1 イデンシ タケイ ト ノ カンレン

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Modern human (homo sapience) have spread out over the world during the ice age, this means they needed to adapt to cold environments. Recent studies suggest that the importance of non-shivering thermogenesis (NST) generating from brown adipose tissue (BAT), and the uncoupling protein 1 (UCP1) gene plays an important role in BAT activity. Thus, this manuscript summarizes the relationship between human cold adaptation and the importance of UCP1 genotype to individual and populational differences of NST.

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