Assessment of the effect and safety of salacinol in horses
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- UEDA Fumitaka
- Bio Science & Engineering Laboratory, Research & Development Management Headquarters, FUJIFILM Corporation, Kanagawa 258-8577, Japan
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- IIDA Atsushi
- Bio Science & Engineering Laboratory, Research & Development Management Headquarters, FUJIFILM Corporation, Kanagawa 258-8577, Japan
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- SAITO Hitomi
- Bio Science & Engineering Laboratory, Research & Development Management Headquarters, FUJIFILM Corporation, Kanagawa 258-8577, Japan
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- SEKI Shinobu
- Bio Science & Engineering Laboratory, Research & Development Management Headquarters, FUJIFILM Corporation, Kanagawa 258-8577, Japan
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- AMAO Akihito
- Highly Functional Materials Business Development Headquarters, FUJIFILM Corporation, Tokyo 107-0052, Japan
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- YAMATE Hirotsugu
- Yamate Racehorse Clinic, Iwate 020-0103, Japan
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Description
<p>We report a study that examined the effect and safety of salacinol from Salacia reticulata extract (SRE) for the intestinal microbiota of horses. We administered SRE to healthy horses and evaluated their intestinal microbiota before and after the test period for changes in composition. Horses that received the SRE showed notable differences in intestinal microbiota composition between before and after administration, with a substantial increase in bacteria of the order Lactobacillales at the end of the test period. Moreover, the Firmicutes-to-Bacteroidetes ratio was elevated. Salacinol was administered as a supplement for 28 days. Physiological and blood tests were conducted in the presence of a veterinarian, and a safety assessment was performed. These evaluations revealed no detrimental findings.</p>
Journal
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- Journal of Equine Science
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Journal of Equine Science 30 (4), 105-111, 2019
Japanese Society of Equine Science
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Details 詳細情報について
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- CRID
- 1390565134806564096
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- NII Article ID
- 130007768881
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- NII Book ID
- AA11010806
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- ISSN
- 13477501
- 13403516
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- NDL BIB ID
- 030149971
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- PubMed
- 31871413
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL Search
- Crossref
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed