Successful Treatment of Anaplastic Lymphoma Kinase (<i>ALK</i>)-rearrangement Atypical Carcinoid of the Lung with an<i> ALK</i> Inhibitor: a Case Report

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  • Takahashi Youhei
    Department of Respiratory Medicine, Kushiro City General Hospital Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine
  • Sudo Yuta
    Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine Department of Respiratory Medicine, Japanese Red Cross Asahikawa Hospital
  • Asai Yuichiro
    Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine
  • Kuronuma Koji
    Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine
  • Chiba Hirofumi
    Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine
  • Takahashi Hiroki
    Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine

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Other Title
  • <i>ALK</i>阻害薬が奏効した<i>ALK</i>融合遺伝子陽性肺異型カルチノイドの1例

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Abstract

<p>Background. Anaplastic lymphoma kinase (ALK)-positive atypical carcinoid of the lung is rare. Case. A 61-year-old man visited a nearby neurosurgery clinic due to nausea and general fatigue. He was admitted to our hospital to undergo neurosurgery for multiple brain tumors and hydrocephalus due to cerebellar lesions. Open brain tumor excision was performed, and the diagnosis, based on a whole body examination, was ALK-rearrangement atypical carcinoid of the lung. ALK inhibitor treatment reduced the size of the lung tumor. Conclusion. We experienced a case in which atypical carcinoid of the lung successfully treated with an ALK inhibitor.</p>

Journal

  • Haigan

    Haigan 59 (7), 1171-1176, 2019-12-20

    The Japan Lung Cancer Society

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