Influence of Percutaneous Occlusion of Atrial Septal Defect on Left Atrial Function Evaluated Using 2D Speckle Tracking Echocardiography

  • Suzuki Kazutaka
    Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences
  • Kato Taichi
    Department of Pediatrics, Nagoya University Graduate School of Medicine
  • Koyama Satoshi
    Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences
  • Shinohara Tsutomu
    Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences
  • Inukai Sachiko
    Department of Pediatrics, Nagoya Daini Red Cross Hospital
  • Sato Jun
    Department of Pediatric Cardiology, Japan Community Healthcare Organization Chukyo Children Heart Center
  • Yamamoto Hidenori
    Department of Pediatrics, Nagoya University Graduate School of Medicine
  • Omori Daisuke
    Department of Pediatrics, Anjo Kosei Hospital
  • Yoshida Shuichiro
    Department of Pediatric Cardiology, Japan Community Healthcare Organization Chukyo Children Heart Center
  • Takeda Sho
    Department of Pediatric Cardiology, Japan Community Healthcare Organization Chukyo Children Heart Center
  • Nishikawa Hiroshi
    Department of Pediatric Cardiology, Japan Community Healthcare Organization Chukyo Children Heart Center
  • Ohashi Naoki
    Department of Pediatric Cardiology, Japan Community Healthcare Organization Chukyo Children Heart Center
  • Sakurai Hajime
    Cardiovascular Surgery, Japan Community Healthcare Organization Chukyo Children Heart Center
  • Saitoh Shinji
    Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences

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Description

<p>Percutaneous occlusion of atrial septal defect (ASD) has recently become a standard therapeutic strategy, but little is known about left atrial (LA) function thereafter. The present study aimed to determine LA function in 43 children with ASD and 13 controls based on LA strain measured by two-dimensional echocardiographic speckle tracking (2DE-ST). Among these children, 12 underwent surgery (ASD-S), 31 had device closure (ASD-D), and 13 were included as controls. LA strain was significantly decreased after ASD-D but was not significantly altered after ASD-S, indicating that percutaneous occlusion of an ASD might decrease LA function. Furthermore, the size of the ASD device negatively correlated with LA strain. These results imply that ASD occlusion devices negatively influence LA function and might be important when decided therapeutic strategies for ASD. LA strain measured by 2DE-ST should become a good indicator of LA function after ASD treatment in children.</p>

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