A Case of Pulmonary Adenocarcinoma with Amylase Production

  • Tani Nozomi
    Department of Respiratory Medicine, University Hospital Kyoto Prefectural University of Medicine
  • Yoshimura Akihiro
    Department of Respiratory Medicine, University Hospital Kyoto Prefectural University of Medicine
  • Harita Sachi
    Department of Respiratory Medicine, University Hospital Kyoto Prefectural University of Medicine
  • Fukui Mototaka
    Department of Respiratory Medicine, University Hospital Kyoto Prefectural University of Medicine
  • Yamada Tadaaki
    Department of Respiratory Medicine, University Hospital Kyoto Prefectural University of Medicine
  • Takayama Koichi
    Department of Respiratory Medicine, University Hospital Kyoto Prefectural University of Medicine

Bibliographic Information

Other Title
  • アミラーゼ産生を伴う肺腺癌の1例

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Description

<p>Background. Amylase-producing lung cancer is resistant to treatment, and serum and urinary amylase (AMY) levels have been reported to reflect the disease state and to be an indicator of treatment efficacy. Case. A man in his 60s visited our hospital due to bloody sputum and an abnormal shadow on chest computed tomography (CT). Chest CT and positron emission tomography-CT showed a consolidation in the right upper lesion, and serum AMY levels were elevated, with the salivary-type enzyme dominating. Based on findings of bronchoscopy and systemic screening, he was diagnosed with advanced AMY-producing pulmonary adenocarcinoma. We performed first-line chemotherapy using cisplatin and pemetrexed. His serum and urinary AMY levels rapidly decreased with a good partial response to chemotherapy. Conclusion. Serum and urinary AMY levels might be useful novel predictive markers in patients with AMY-producing pulmonary adenocarcinoma.</p>

Journal

  • Haigan

    Haigan 60 (1), 48-53, 2020-02-20

    The Japan Lung Cancer Society

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