神経障害性疼痛治療薬プレガバリン（リリカ<sup>®</sup>）の開発

DOI

書誌事項

タイトル別名
  • Development history of pregabalin（Lyrica）

この論文をさがす

説明

<p>Neuropathic pain is now defined by the International Association for the Study of Pain as pain caused by a lesion or disease of the somatosensory nervous system. The guidelines recommend tricyclic antidepressants, gabapentin or pregabalin, and duloxetine, a serotonin noradrenaline reuptake inhibitor, as first line. Mirogabalin, which is a novel ligand for the α2δ subunit of voltage-gated calcium channels, is being developed for treating neuropathic pain including diabetic peripheral neuropathy and postherpetic neuralgia. In this review, serendipitous discovery of pregabarin by Richard Silverman is discussed.</p>

収録刊行物

  • 歯科薬物療法

    歯科薬物療法 38 (3), 191-194, 2019

    日本歯科薬物療法学会

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ