Anti-myelin oligodendrocyte glycoprotein antibody-positive neurologic disease, manifested as clinical course of classical Devic’s disease: A case report
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- Oji Satoru
- Department of Neurology, Saitama Medical Center, Saitama Medical University
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- Yamaga Tetsuo
- Department of Neurology, Saitama Medical Center, Saitama Medical University
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- Suzuki Masato
- Department of Neurology, Saitama Medical Center, Saitama Medical University
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- Tanaka Satoru
- Department of Neurology, Saitama Medical Center, Saitama Medical University
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- Fukaura Hikoaki
- Department of Neurology, Saitama Medical Center, Saitama Medical University
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- Nomura Kyoichi
- Department of Neurology, Saitama Medical Center, Saitama Medical University
Bibliographic Information
- Other Title
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- Devic病と類似した臨床経過を呈した抗myelin oligodendrocyte glycoprotein抗体陽性神経疾患の1例
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Abstract
<p>A 33-year-old male was admitted to our hospital due to bilateral optic neuritis (ON) and transverse myelitis (TM), which occurred almost simultaneously. Spinal MRI showed the longitudinally extensive TM, located from C2 to conus. Serum anti-aquaporin 4 antibody was negative. He was tentatively diagnosed as seronegative neuromyelitis optica spectrum disorders (NMOSD). During the clinical course, serum anti-myelin oligodendrocyte glycoprotein (MOG) antibody was detected, and finally he was diagnosed as anti-MOG antibody positive neurologic disease (MOG-ND). Our case highlighted that early detection of MOG antibody should be considered in male cases with clinical manifestation of classical Devic’s disease, such as simultaneous disease onset of bilateral ON or ON + TM.</p>
Journal
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- Rinsho Shinkeigaku
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Rinsho Shinkeigaku 60 (3), 219-222, 2020
Societas Neurologica Japonica