Post Menopausal Woman with Breast Cancer Treated with Androgen for Gender Identity Disorder

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  • 性同一性障害に対するアンドロゲン投与中に発生した閉経後乳癌の1例
  • 症例 性同一性障害に対するアンドロゲン投与中に発生した閉経後乳癌の1例
  • ショウレイ セイ ドウイツセイ ショウガイ ニ タイスル アンド ロゲン トウヨ チュウ ニ ハッセイ シタ ヘイケイ ゴ ニュウガン ノ 1レイ

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<p>A 54-year-old postmenopausal woman with gender identity disorder was administered androgen as part of the female-to-male transformation. Right breast calcification was detected during breast cancer screening, and she underwent physical examination at a local hospital. She was diagnosed with mucinous carcinoma via needle biopsy under stereotactic guidance. With a pre-operative diagnosis of T1N0M0 Stage IA, she underwent a total mastectomy with sentinel lymph node biopsy. Histological examination revealed mucinous carcinoma (pT1cN0M0 Stage IA), ER (score 5), PgR (score 5), HER2 (1+), and Ki-67 index (1%). At the patient's request, androgen supplementation was re-started after the surgery. The occurrence of breast cancer during androgen administration for gender identity disorder is extremely rare. The mechanism and clinical outcome will be evaluated after further data collection.</p>

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