ANALYSIS OF ACUTE MYELOID LEUKEMIA IN SHOWA UNIVERSITY HOSPITAL IN PAST TEN YEARS

DOI
  • YANAGISAWA Kouji
    Department of Medicine, Division of Hematology, Showa University School of Medicine
  • HATTORI Norimichi
    Department of Medicine, Division of Hematology, Showa University School of Medicine
  • WATANUKI Megumi
    Department of Medicine, Division of Hematology, Showa University School of Medicine
  • FUJIWARA Shun
    Department of Medicine, Division of Hematology, Showa University School of Medicine
  • ARAI Nana
    Department of Medicine, Division of Hematology, Showa University School of Medicine
  • TSUKAMOTO Hiroyuki
    Department of Medicine, Division of Hematology, Showa University School of Medicine
  • SAITO Bungo
    Department of Medicine, Division of Hematology, Showa University School of Medicine
  • NAKAMAKI Tsuyoshi
    Department of Medicine, Division of Hematology, Showa University School of Medicine

Bibliographic Information

Other Title
  • 昭和大学血液内科における急性骨髄性白血病の後方視的解析

Description

We retrospectively analyzed the pathology and prognosis of 111 pts with acute myeloid leukemia （AML） in the past 10 years in the Showa University Hospital; 52.2％ of the patients was over 65 years old and 28.8％ had a diagnosis of AML with MRC. Overall survival （OS） was 34.5％ and median survival time was 22 months. Multivariate analysis showed that age and gender significantly influenced OS of patients. Except for t（15；17）, the significance of karyotype was limited. SCT did not significantly improve OS of AML. Introduction of a further targeted therapy based on the molecular pathology and a decrease non-relapse mortality in SCT appeared to be important to improve survival of AML of high age elderly.

Journal

Keywords

Details 詳細情報について

  • CRID
    1390566775133591040
  • NII Article ID
    130007841705
  • DOI
    10.14930/jshowaunivsoc.79.725
  • ISSN
    2188529X
    2187719X
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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