A clinical case of T-cell lymphoma with co-expression of a B-cell marker in a Holstein cow
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- Maezawa M.
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine United Graduate School of Veterinary Sciences, Gifu University
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- Kudo N.
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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- Temma S.
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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- Sekizuka J.
- Urahoro Branch, Tokachi Agricultural Mutual Aid Association
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- Watanabe K.
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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- Horiuchi N.
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine United Graduate School of Veterinary Sciences, Gifu University
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- Matsumoto K.
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine United Graduate School of Veterinary Sciences, Gifu University
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- Kobayashi Y.
- Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine United Graduate School of Veterinary Sciences, Gifu University
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- Inokuma H.
- Veterinary Medical Center, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Bibliographic Information
- Other Title
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- ホルスタイン種乳用牛におけるB 細胞マーカーの共発現を伴う T 細胞性リンパ腫の1 症例
- 症例報告 日本家畜臨床学会 第50回学術集会 最優秀発表賞受賞演題 ホルスタイン種乳用牛におけるB細胞マーカーの共発現を伴うT細胞性リンパ腫の1症例
- ショウレイ ホウコク ニホン カチク リンショウ ガッカイ ダイ50カイ ガクジュツ シュウカイ サイユウシュウ ハッピョウショウ ジュショウ エンダイ ホルスタインシュ ニュウヨウギュウ ニ オケル Bサイボウ マーカー ノ キョウ ハツゲン オ トモナウ Tサイボウセイ リンパシュ ノ 1 ショウレイ
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Abstract
<p> A 5-year-and-2-month-old Holstein cow was presented with a cervical mass. Physical examination revealed a left cervical mass and enlarged superficial lymph nodes. By fine needle aspiration cytology of the left superficial cervical lymph node, approximately 70% of cells were medium or large atypical lymphoid cells. Hematology and serum biochemical findings included elevated lymphocyte count, lactate dehydrogenase activity and thymidine kinase activity. Nested polymerase chain reaction for bovine leukemia virus(BLV)and antibody against BLV were both negative. During necropsy, masses were found in the left cervical, left pectoral, left axillary regions and in the abdominal and pelvic cavities. Generalized lymphadenopathy was also noted. Histopathological examination showed solitary proliferation of large round neoplastic cells. By immunohistochemistry, most of the neoplastic cells were positive for CD3, and some were positive for BLA-36 and CD20. Double immunofluorescence confirmed co-expression of CD3 and BLA-36 in neoplastic cells. The cow was diagnosed with T-cell lymphoma with co-expression of a B-cell marker.</p>
Journal
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- Japanese Journal of Large Animal Clinics
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Japanese Journal of Large Animal Clinics 11 (1), 17-21, 2020-04-30
Japanese Society of Large Animal Clinics / Large Animal Clinic Research Association
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Keywords
Details 詳細情報について
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- CRID
- 1390566775142517504
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- NII Article ID
- 130007856550
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- NII Book ID
- AA12483687
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- ISSN
- 21872805
- 1884684X
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- NDL BIB ID
- 030430139
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- Text Lang
- ja
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed