A Case of Hangekobokuto Improved Dysphagia and Aspiration Pneumonia Considered to be Caused by Late-Stage Neurosyphilis
-
- HAMAGUCHI Shinsuke
- Department of Anesthesiology and Pain Medicine, Dokkyo Medical University School of Medicine
-
- KANEKO Toru
- Kaneko Ear, Nose and Throat Clinic
-
- SHIMIZU Ihane
- Toyodo Utsunomiya Clinic
-
- KIMURA Hiromi
- Toyodo Utsunomiya Clinic
Bibliographic Information
- Other Title
-
- 後期神経梅毒が原因と考えられた嚥下障害と誤嚥性肺炎の改善に半夏厚朴湯が有効であった1例
- 臨床報告 後期神経梅毒が原因と考えられた嚥下障害と誤嚥性肺炎の改善に半夏厚朴湯が有効であった1例
- リンショウ ホウコク コウキ シンケイ バイドク ガ ゲンイン ト カンガエラレタ エンカ ショウガイ ト ゴエンセイ ハイエン ノ カイゼン ニ ハンゲコウボクトウ ガ ユウコウ デ アッタ 1レイ
Search this article
Description
<p>We investigated the effectiveness of hangekobokuto in alleviating dysphagia and aspiration pneumonia attributed to latestage neurosyphilis. Our study subject, a 67-year-old man treated for his leg pain in our department, hoped this treatment would relieve his severe cough and sore throat. According to a neurological investigation and the analysis of blood and cerebrospinal fluid, his symptoms (swallowing disturbance and aspiration pneumonia in the lower lobes of both lungs) led to the diagnosis of cerebral bulbar paralysis caused by latestage neurosyphilis. The patient requested drug therapy ; thus, we prescribed 7.5 g/day of hangekobokuto, to be administered orally, based on his medical findings of qi stagnation and tan yin. Dysphagia was relieved one week after oral administration of hangekobokuto, and after three weeks, the patient's discomfort had almost disappeared. Moreover, aspiration pneumonia was also improved in his chest CT image finding. Late-stage neurosyphilis symptoms usually develop within 20 to 30 years of contracting syphilis, an infection caused by the bacterium Treponema pallidum. Symptoms may include a loss of swallowing reflex and cough reflex due to the paralysis of cerebral basal ganglia. However, hangekobokuto was found to increase the concentration of substance P released in the pharyngeal head and tracheal mucosa, and thus improve swallowing function. We conclude that hangekobokuto is a useful agent for alleviating the swallowing abnormality of late-stage neurosyphilis.</p>
Journal
-
- Kampo Medicine
-
Kampo Medicine 71 (1), 36-40, 2020
The Japan Society for Oriental Medicine
- Tweet
Details 詳細情報について
-
- CRID
- 1390566775149230208
-
- NII Article ID
- 130007869088
-
- NII Book ID
- AN00015774
-
- ISSN
- 1882756X
- 02874857
-
- NDL BIB ID
- 030270780
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed