オトガイ部に発生した結節性筋膜炎の1例

  • 田中 美佐子
    東京医科歯科大学大学院医歯学総合研究科顎口腔外科学分野
  • 富岡 寛文
    東京医科歯科大学大学院医歯学総合研究科顎口腔外科学分野
  • 高原 楠旻
    東京医科歯科大学大学院医歯学総合研究科顎顔面外科学分野
  • 畠山 一郎
    東京医科歯科大学大学院医歯学総合研究科顎口腔外科学分野
  • 坂本 啓
    東京医科歯科大学大学院医歯学総合研究科口腔病理学分野
  • 原田 浩之
    東京医科歯科大学大学院医歯学総合研究科顎口腔外科学分野

書誌事項

タイトル別名
  • A case of nodular fasciitis occurring in the mental region
  • オトガイブ ニ ハッセイ シタ ケッセツセイキンマクエン ノ 1レイ

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<p>Nodular fasciitis is a reactive proliferative lesion arising from the fascia. The predilection site is the upper extremity or trunk. Nodular fasciitis arising in the head and neck region is rare. We report a case of nodular fasciitis occurring in the mental region. A 33-year-old woman was referred to our department because of a mental region mass. The mass was located in the subcutaneous tissue of the left mental region, and it was painless, elastic hard, and measured 18 × 14-mm. Computed tomography and magnetic resonance imaging revealed that no obvious bone resorption in the mandible. For a diagnosis of a left mental region tumor, we performed tumor resection with the patient under general anesthesia. Histopathological examination showed a dense, loose proliferation of spindle cells. Immunohistochemical study revealed that the cells were positive for α-SMA, and negative for CD34, desmin, S-100, β -catenin, STAT6, and ALK. The Ki-67 labeling index was 10%. The presence of the MYH9-USP6 fusion gene was analyzed by reverse transcription polymerase chain reaction, but was not found. Nodular fasciitis was diagnosed histopathologically. There was no recurrence for 5 years 3 months after operation.</p>

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