A Case of Rosai-Dorfman Disease Arising from the Parotid Gland

DOI Web Site Web Site

Bibliographic Information

Other Title
  • 耳下腺に生じたRosai-Dorfman病例
  • 臨床 耳下腺に生じたRosai-Dorfman病例
  • リンショウ ジカセン ニ ショウジタ Rosai-Dorfmanビョウレイ

Search this article

Abstract

<p>Rosai-Dorfman disease (RDD) is a rare type of histiocytosis that was first reported as sinus histiocytosis with massive lymphadenopathy by Rosai and Dorfman in 1969. We report the case of a 77-year-old man who presented with a 2-month history of left parotid enlargement. Blood examination showed an elevated serum level of soluble interleukin-2 receptor. Fine needle aspiration cytology of the left parotid gland nodule showed many lymphocytes without atypia. Therefore, we suspected of malignant lymphoma and performed left partial parotidectomy for obtaining a definitive diagnosis. The histopathologic diagnosis was RDD. Because the patient had no symptoms or vital organ involvement, he has been under close observation for 15 months since.</p><p>The preoperative diagnosis of RDD is difficult, but if the characteristic finding of emperipolesis can be recognized in fine needle aspiration cytology, it may be possible to diagnose RDD before surgery. In patients with a histopathologic diagnosis of RDD, it is necessary to perform a full body search at regular intervals to determine whether treatment is necessary, because the prognosis is poor in some cases.</p>

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top