Review of 13 cases of descending necrotizing mediastinitis -Importance of understanding the pathway-

  • Yamada Kyoko
    Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine
  • Shimizu Kimihiro
    Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine
  • Koyama Tsutomu
    Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine
  • Matsuoka Shunichiro
    Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine
  • Takeda Tetsu
    Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine
  • Eguchi Takashi
    Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine
  • Hamanaka Kazutoshi
    Division of General Thoracic Surgery, Department of Surgery, Shinshu University School of Medicine

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Other Title
  • 降下性壊死性縦隔炎13例の検討―進展経路認識の重要性―

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<p>Descending necrotizing mediastinitis (DNM) is an illness typically caused by pharyngeal and odontogenic infections spreading to the mediastinum, which can follow a severe and sometimes fatal course. Here, we examined the clinical course of 13 patients who underwent mediastinal drainage in our hospital. Out of the 13 patients, 12 underwent thoracoscopic mediastinal drainage with an approach from the right thoracic cavity. Two cases had undergone cervical drainage in an otolaryngology department before extension into the mediastinum was observed, and thus mediastinal drainage was performed as a secondary surgery. The mean length of the post-operative hospital stay was long, at 46 days. There was a single case of postoperative mortality, involving a patient who had to wait approximately 2 weeks before receiving a diagnosis. A definitive consensus on drainage methods and approaches for treating DNM has not yet been reached.</p><p>Nevertheless, early diagnosis and less invasive surgical mediastinal drainage using a thoracoscopic approach are considered beneficial for improving the survival rate in patients with DNM. Further, identifying the route of extension by CT can help predict subsequent disease progression to some degree, which can be useful for selecting the optimal surgical modality.</p>

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