Condyloma acuminatum of the nipple resembling seborrheic keratosis

DOI Web Site Web Site 9 References Open Access
  • Murao Kazutoshi
    Department of Dermatology, Tokushima University Graduate School of Medical Science
  • Kubo Yoshiaki
    Department of Dermatology, Tokushima University Graduate School of Medical Science

Bibliographic Information

Other Title
  • 乳頭に生じ脂漏性角化症様の外観を呈した尖圭コンジローマの1例
  • ニュウトウ ニ ショウジ シロウセイ カッカショウ サマ ノ ガイカン オ テイシタ セン ケイ コンジローマ ノ 1レイ

Search this article

Description

A 25-year-old Japanese female presented with a skin lesion on her left nipple. The lesion had been present for three months and was increasing in size. A physical examination revealed a brown hyperkeratotic verrucous nodule on her left nipple. A histological examination of a biopsy specimen showed hyperkeratosis, papillo-matosis, and acanthosis. There were several koilocytes in the upper epidermis. Positive staining for human papillomavirus (HPV) particles by immunohistochemical analysis was seen in several cell nuclei at the upper malpighian layer. Mucous-type HPV DNA was detected in the lesion using the polymerase chain reaction (PCR), and it was identified as HPV type 6 by direct sequencing of the PCR product. We treated the patient by cryotherapy with liquid nitrogen, and the lesion disappeared. Condyloma acuminatum of the nipple is very rare. Interestingly, most reported clinical cases exhibit a seborrheic keratosis-like appearance. Dermatologists should consider condyloma acuminatum in cases in which seborrheic keratosis-like lesions are shown on the nipple.

Journal

References(9)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top