A Patient with Necrotizing Vasculitis Related to Sarcoidosis, which Was Diagnosed via Immunohistochemical Methods Using Propionibacterium acnes-specific Monoclonal Antibodies
-
- Noda Seiji
- Department of Rheumatology, Ome General Municipal Hospital, Japan
-
- Maeda Ayaka
- Department of Rheumatology, Ome General Municipal Hospital, Japan
-
- Komiya Yoji
- Department of Rheumatology, Ome General Municipal Hospital, Japan
-
- Soejima Makoto
- Department of Rheumatology, Ome General Municipal Hospital, Japan
書誌事項
- タイトル別名
-
- A Patient with Necrotizing Vasculitis Related to Sarcoidosis, which Was Diagnosed via Immunohistochemical Methods Using <i>Propionibacterium acnes</i>-specific Monoclonal Antibodies
この論文をさがす
説明
<p>Propionibacterium acnes (P. acnes) is a commensal bacterium indigenous to the skin. Previous reports have suggested that infection with P. acnes causes sarcoidosis, a systemic granulomatous disease. We present the case of a 63-year-old woman who developed subcutaneous nodules. A skin biopsy revealed necrotizing vasculitis and noncaseating granulomas, which are characteristic of sarcoidosis. Immunohistostaining revealed a P. acnes skin infection, which led to the diagnosis of sarcoidosis. Minocycline treatment resolved the infection and improved the patient's symptoms. We herein report a case in which immunohistochemistry was useful in the diagnosis of sarcoidosis. </p>
収録刊行物
-
- Internal Medicine
-
Internal Medicine 59 (19), 2423-2425, 2020-10-01
一般社団法人 日本内科学会