Simultaneous Determination of Arbutin and Hydroquinone in Dried Bearberry Leaf Extracts by HPLC

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Other Title
  • HPLCによるウワウルシ乾燥エキス中のアルブチンおよびヒドロキノンの同時定量
  • アナリティカルレポート 若手初論文 HPLCによるウワウルシ乾燥エキス中のアルブチンおよびヒドロキノンの同時定量
  • アナリティカルレポート ワカテ ハツ ロンブン HPLC ニ ヨル ウワウルシ カンソウ エキス チュウ ノ アルブチン オヨビ ヒドロキノン ノ ドウジ テイリョウ

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Description

<p>Recently, a plain extract bearberry leaf formulation was proven to be an “efficacious treatment for feeling of incomplete emptying and discomfort during urination”. Therefore, this formulation can be considered for commercialization as an over-the-counter (OTC) drug. However, before obtaining approval for selling this formulation, it is necessary to first examine its quality control-related characteristics. Hence, in the current study we established a method for the quantitation of arbutin and hydroquinone in plain extract bearberry formulation. Moreover, we compared the contents of the plain extract bearberry leaf tablet after storage in a brown bottle or aluminum package to determine the storage characteristics.</p>

Journal

  • BUNSEKI KAGAKU

    BUNSEKI KAGAKU 69 (7.8), 357-362, 2020-07-05

    The Japan Society for Analytical Chemistry

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