Evaluation of the Effect of Lentinula Edodes Mycelia Extract on Immune Function in Healthy Subjects Placebo-controlled, Parallel-group Study
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- KAJIYAMA Shota
- Central R&D Laboratory, KOBAYASHI Pharmaceutical Co., Ltd.
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- MATSUI Yasunori
- Central R&D Laboratory, KOBAYASHI Pharmaceutical Co., Ltd.
Bibliographic Information
- Other Title
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- シイタケ菌糸体抽出物の健常者に対する免疫機能に及ぼす影響検証:プラセボ対照並行群間比較試験
- シイタケ キンシタイ チュウシュツブツ ノ ケンジョウシャ ニ タイスル メンエキ キノウ ニ オヨボス エイキョウ ケンショウ : プラセボ タイショウ ヘイコウグン カン ヒカク シケン
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Abstract
In this study, we examined the effects of Lentinula edodes mycelia (LEM) on fatigue and immune function in healthy subjects. 22 people were randomly assigned in a 1:1 ratio to the LEM ingestion group and the placebo group. Daily oral ingestion of LEM for 4 weeks (600 mg/day) significantly improved the VAS fatigue score compared with before treatment (p<0.01). Additionally, NK cell activity was increased by ingestion of LEM (p<0.01) and was higher level compared to the placebo group (p<0.05). These results indicate that oral ingestion of LEM may improve the feeling of fatigue and immune function.
Journal
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- Japanese Journal of Complementary and Alternative Medicine
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Japanese Journal of Complementary and Alternative Medicine 17 (2), 105-110, 2020-12-14
The Japanese Society for Complementary and Alternative Medicine
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Details 詳細情報について
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- CRID
- 1390568456351375488
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- NII Article ID
- 130007967138
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- NII Book ID
- AA12095429
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- ISSN
- 13487930
- 13487922
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- NDL BIB ID
- 031234949
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed