Perioperative Management of Congenital Aberrant Fibrinogenemia Using Rotational Thromboelastometry（ROTEM）

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  • SAKAMOTO Shotaro
    Department of Anesthesiology, Kyoto Prefectural University of Medicine
  • SHIMIZU Masaru
    Department of Anesthesiology, Kyoto Prefectural University of Medicine
  • KINOSHITA Mao
    Department of Anesthesiology, Kyoto Prefectural University of Medicine
  • ISHIMARU Toshiki
    Department of Anesthesiology, Kyoto Prefectural University of Medicine
  • SASAKAWA Nao
    Department of Anesthesiology, Japanese Red Cross Kyoto Daiichi Hospital
  • SAWA Teiji
    Department of Anesthesiology, Kyoto Prefectural University of Medicine

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  • ローテーショナルトロンボエラストメトリー（ROTEM）を用いた先天性フィブリノゲン異常症の周術期管理

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<p>Congenital aberrant fibrinogenemia is an extremely rare hemorrhagic disease. In this case, we treated our patient with concentrated fibrinogen preoperatively because of a low plasma fibrinogen level of 52 mg/dL and a high risk of bleeding. In addition to the standard coagulation tests, we used rotational thromboelastometry（ROTEM）, which allows us to confirm coagulation ability before and after administration of concentrated fibrinogen. We performed perioperative management without any problems. ROTEM can identify the necessary minimum coagulation factors and reduce the risk of thrombotic and embolic complications due to overdose of clotting factors and is useful for perioperative management.</p>

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