A Report on Changes in The Viral Load in Pharyngeal and Nasopharyngeal Swab Specimens in A Patient with Community-acquired Coronavirus Infection 2019 (COVID-19)

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  • MIYAJIMA Makiko
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine
  • NAKAHARAI Kazuhiko
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine
  • HOSHINA Tokio
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine
  • NAKAZAWA Yasushi
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine Department of Infection Control, Jikei University Hospital
  • MISHIMA Yukie
    Department of Infection Control, Jikei University Hospital
  • SAWAKI Kenji
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine
  • SAKAMOTO Yohei
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine
  • LEE Kwangyeol
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine
  • HOSAKA Yumiko
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine
  • HORINO Tetsuya
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine
  • YOSHIDA Masaki
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine
  • HORI Seiji
    Department of Infectious Diseases and Infection Control, Jikei University School of Medicine

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Other Title
  • 市中感染の新型コロナウイルス感染症（COVID-19）患者における咽頭および鼻咽頭拭い液でのウイルス量の推移に関する報告
  • 症例 市中感染の新型コロナウイルス感染症(COVID-19)患者における咽頭および鼻咽頭拭い液でのウイルス量の推移に関する報告
  • ショウレイ シ ジュウ カンセン ノ シンガタ コロナウイルス カンセンショウ(COVID-19)カンジャ ニ オケル イントウ オヨビ ハナ イントウ ヌグイ エキ デ ノ ウイルスリョウ ノ スイイ ニ カンスル ホウコク

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Abstract

<p>Coronavirus infection 2019 (COVID-19) is a respiratory infection caused by a novel coronavirus (SARS-CoV-2) that was first reported in Wuhan, China, in December 2019. In Japan, since mid-February 2020, there have been a series of reports of COVID-19 outbreaks among people without apparent contact with COVID-19 patients or visitors to Japan from endemic areas, or a recent history of visiting an endemic area. We encountered a patient with COVID-19 arising from local community transmission of infection, who presented with the chief complaints of fatigue and anorexia. In this patient, a quantitative polymerase chain reaction (PCR) assay showed a higher viral load and a more extended period of viral excretion in nasopharyngeal swab specimens than in pharyngeal swab specimens. When using a PCR assay as a diagnostic test or as an indicator of improvement, we should be aware of the characteristics and limitations of the test.</p>

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 94 (4), 587-590, 2020-07-20

    The Japanese Association for Infectious Diseases

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