Development and functional analysis of novel HER3/HRG interaction inhibitors for cancer treatment

  • Ando Takehiro
    Dept. Life Environ. Sci., Integr. Grad. Sch. Med. Eng. Agr. Sci., Yamanashi Univ.
  • Yokoyama Takumi
    Dept. Life Environ. Sci., Integr. Grad. Sch. Med. Eng. Agr. Sci., Yamanashi Univ.
  • Iwamoto Rina
    Dept. Life Environ. Sci., Integr. Grad. Sch. Med. Eng. Agr. Sci., Yamanashi Univ.
  • Fuji Daisuke
    Dept. Biotechnol., Fac. Life Environ. Sci., Yamanashi Univ.
  • Yamamoto Mizuki
    Dept. Integr. Appl. Life Sci., Integr. Grad. Sch. Med. Eng. Agr. Sci., Yamanashi Univ.
  • Kawakami Takashi
    Fac. Life Environ. Sci., Grad. Fac. Interdiscip. Res., Yamanashi Univ. JST, PRESTO

Bibliographic Information

Other Title
  • がん分子標的治療のための新規HER3/HRG間相互作用阻害剤の開発と機能解析

Abstract

<p>Here, we report the discovery of novel HER3/HRG interaction inhibitors that bind to HER3 by using the mRNA display evolution based on an Escherichia coli reconstituted cell-free translation system (PURE system) and functional analysis of the inhibitors.</p>

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