A Case of Secondary Alveolar Proteinosis Requiring Segmental Bronchoalveolar Lavage
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- Hida Norihito
- Department of Respiratory Medicine, Hitachi Ltd., Hitachinaka General Hospital
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- Yamada Hideyasu
- Department of Respiratory Medicine, Hitachi Ltd., Hitachinaka General Hospital Department of Pulmonary Medicine, University of Tsukuba
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- Mase Kentaro
- Department of Surgery, Hitachi Ltd., Hitachinaka General Hospital
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- Hizawa Nobuyuki
- Department of Pulmonary Medicine, University of Tsukuba
Bibliographic Information
- Other Title
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- 気管支鏡下での区域洗浄を要した続発性肺胞蛋白症の1例
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Abstract
<p>Background. Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by alveoli filled with PAS-positive surfactants and phospholipids. We herein report an immunosuppressive patient with secondary PAP who was successfully treated by segmental bronchoalveolar lavage (BAL) without any complications. Case. A 54-year-old Japanese man was admitted to our hospital because of a cough during immunosuppressive therapy for Takayasu's arteritis and was hospitalized for suspected acute interstitial pneumonia based on chest X-ray and computed tomography (CT) findings of ground-glass opacities in both lung fields. Broad-spectrum antibiotics, antifungal drugs, and corticosteroids were ineffective, and the diagnosis of PAP was made by a thoracoscopic lung biopsy. Following segmental BAL, his respiratory condition and ground-glass opacity in both lung fields improved with no recurrence. Conclusion. Although whole-lung lavage under general anesthesia is often used as a standard treatment for alveolar proteinosis, even in cases of immunosuppressed hosts with secondary alveolar proteinosis, such as the present patient, segmental BAL is used. A comprehensive approach that includes segmental BAL is necessary.</p>
Journal
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- The Journal of the Japan Society for Respiratory Endoscopy
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The Journal of the Japan Society for Respiratory Endoscopy 43 (2), 123-128, 2021-03-25
The Japan Society for Respiratory Endoscopy
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Details 詳細情報について
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- CRID
- 1390569070680974336
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- NII Article ID
- 130008021166
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- ISSN
- 21860149
- 02872137
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed