Virus Cell Biology and Microscopy

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  • Yamauchi Yohei
    英国ブリストル大学生命科学部細胞分子医学科・名古屋大学理学部生命理学科

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Other Title
  • ウイルス細胞生物学と顕微鏡法
  • ウイルス サイボウ セイブツガク ト ケンビキョウホウ

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Abstract

<p>Viruses are infectious agents that have genomic information encapsulated within a protective shell and often enveloped with a lipid bilayer from the host cell. An infected cell is transformed into a viral factory and literally hijacked by the virus. As viruses are small, 5–300 nm in size and uniform they are ideal for visualisation using microscopy of all kinds including light microscopy, electron microscopy, cryo electron microscopy and atomic force microscopy. Our laboratory is interested in the cell biology of virus infections and virus-host interactions during viral entry into host cells at the molecular level. By deeply understanding virus cell biology, we can target essential virus-host interactions and formulate antiviral strategies that complement vaccines in the future. Here, I would like to introduce some of the microscopy techniques used in our work on influenza A virus and SARS-CoV-2.</p>

Journal

  • KENBIKYO

    KENBIKYO 56 (1), 23-30, 2021-04-30

    The Japanese Society of Microscopy

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