Incremental Predictive Value of Coronary Calcium Score in Risk Stratification of Coronary Revascularization in Patients With Normal or Mild Ischemia Using Nuclear Myocardial Perfusion Single Photon Emission Computed Tomography
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- Suzuki Yasuyuki
- Department of Cardiology, Nihon University Hospital
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- Matsumoto Naoya
- Department of Cardiology, Nihon University Hospital
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- Matsuo Rei
- Department of Cardiology, Nihon University Hospital
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- Nagumo Sakura
- Department of Cardiology, Showa University Fujigaoka Hospital
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- Kuronuma Keiichiro
- Department of Cardiology, Kawaguchi Municipal Medical Center
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- Ashida Tadashi
- Department of Cardiology, Nihon University Hospital
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- Yoda Shunichi
- Division of Cardiology, Department of Medicine, Nihon University
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- Tani Shigemasa
- Department of Cardiology, Nihon University Hospital
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- Amano Yasuo
- Department of Radiology, Nihon University Hospital
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- Okumura Yasuo
- Division of Cardiology, Department of Medicine, Nihon University
書誌事項
- 公開日
- 2021-05-25
- 資源種別
- journal article
- DOI
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- 10.1253/circj.cj-20-0805
- 公開者
- 一般社団法人 日本循環器学会
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説明
<p>Background:The incremental predictive value of the coronary artery calcium score (CACS) for risk stratification of coronary revascularization in patients with normal or mildly abnormal nuclear myocardial perfusion single photon emission computed tomography (MPS) scores is unknown.</p><p>Methods and Results:We analyzed 528 patients in whom CACS was calculated and who underwent stress MPS within 3 months. Patients with known coronary artery disease, prior coronary revascularization, and those undergoing hemodialysis were excluded. Patients were followed-up with coronary revascularization based on the evidence of physiological ischemia defined by fractional flow reserve or severe coronary stenosis (≥90%). CACS was significantly associated with the summed stress score (SSS) from MPS assessment. Multivariate logistic regression analysis showed that high CACS (≥300; odds ratio [OR] 5.44, 95% confidence interval [CI] 2.28–13.0) and SSS (OR 1.29, 95% CI 1.18–1.40) were significant (P<0.001) predictors of future coronary revascularization. The log-rank test showed that high CACS stratified coronary revascularization in normal SSS (0–3; P<0.001) or mildly abnormal SSS (4–8; P=0.028) groups, whereas high CACS did not significantly stratify coronary revascularization in moderate to severe SSS (≥9; P=0.757).</p><p>Conclusions:Risk stratification using CACS with a cut-off value 300 may have incremental predictive value for revascularization in patients with normal or mildly abnormal MPS.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 85 (6), 877-882, 2021-05-25
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390569612379991808
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- NII論文ID
- 130008043209
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 031476039
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- PubMed
- 33504711
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- PubMed
- CiNii Articles
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