A case of diffuse large B-cell lymphoma with Warthin’s tumor in the parotid gland

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  • Matsumoto Hayato
    Department of Otolaryngology Head and Neck Surgery, Kagoshima University Graduate School of Medical and Dental Sciences
  • Nagano Hiromi
    Department of Otolaryngology Head and Neck Surgery, Kagoshima University Graduate School of Medical and Dental Sciences
  • Umakoshi Mizuo
    Department of Otolaryngology Head and Neck Surgery, Kagoshima University Graduate School of Medical and Dental Sciences
  • Kawabata Masaki
    Department of Otolaryngology Head and Neck Surgery, Kagoshima University Graduate School of Medical and Dental Sciences
  • Kurono Yuichi
    Department of Otolaryngology Head and Neck Surgery, Kagoshima University Graduate School of Medical and Dental Sciences

Bibliographic Information

Other Title
  • びまん性大細胞型B細胞リンパ腫を合併した耳下腺Warthin腫瘍の1例
  • ビマンセイ ダイ サイボウガタ Bサイボウ リンパシュ オ ガッペイ シタ ジカセン Warthin シュヨウ ノ 1レイ

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Abstract

We report a case of diffuse large B-cell lymphoma arising from Warthin’s tumor in the parotid gland. An 8X-year-old man presented with a mass in the right side of the parotid gland which was painful and gradually enlarged over two months. CT showed a uniform region in the parotid gland. A positron emission tomography/computed tomography （PET/CT） scan showed abnormal accumulation in the same area. The histological diagnosis was Warthin’s tumor in the first biopsy. However, since the tumor was rapidly enlarging, a second biopsy was performed. Histological analysis showed variant cell, which stained positively for CD20, CD25, and CD79 and negatively for CD3, CD4, and CD8, and the tumor was diagnosed as malignant lymphoma, diffuse large B-cell type. Taking those findings together, we diagnosed the patient as malignant lymphoma with Warthin’s tumor in the parotid gland.

Journal

  • Stomato-pharyngology

    Stomato-pharyngology 33 (2), 65-70, 2020

    Japan Society of Stomato-pharyngology

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