Association between delivery and menopause, and arteriosclerosis among the Japanese general women

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  • Nishino Kayoko
    Department of Social Medicine, Hirosaki University Graduate School of Medicine Department of Health Promotion, Hirosaki University Graduate School of Health
  • Takahashi Ippei
    Department of Social Medicine, Hirosaki University Graduate School of Medicine
  • Umeda Takashi
    Department of Social Medicine, Hirosaki University Graduate School of Medicine
  • Danjo Kazuma
    Department of Social Medicine, Hirosaki University Graduate School of Medicine
  • Matsuzaka Masashi
    Department of Social Medicine, Hirosaki University Graduate School of Medicine
  • Tsuya Ryosuke
    Department of Social Medicine, Hirosaki University Graduate School of Medicine
  • Nakaji Shigeyuki
    Department of Social Medicine, Hirosaki University Graduate School of Medicine

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Other Title
  • 分娩と閉経が動脈硬化に及ぼす影響
  • ブンベン ト ヘイケイ ガ ドウミャク コウカ ニ オヨボス エイキョウ

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Abstract

    The relationship between delivery/menopause and arteriosclerosis has received much attention. The authors examined this relationship in the Japanese general female population. The subjects of the study comprised 735 women who participated in the Iwaki Health Promotion Project between 2006 and 2009. Lifestyle, reproduction history, serum parameters (LDL-cholesterol, HbA1c etc.) and brachial-ankle pulse wave velocity (baPWV) were surveyed. baPWV, systolic blood pressure (SBP), LDL-cholesterol and HbA1c were higher in the menopause group than in the non-menopause group. The higher the number of deliveries, the higher was the baPWV, SBP and HbA1c. In the non-delivery group, baPWV, LDL-cholesterol and HbA1c were higher in the menopause group than in the non-menopause group. In the delivery group, in addition to the previous three factors, SBP was higher in the menopause group than in the non-menopause group. In both the menopause and non-menopause groups, baPWV and SBP were higher in the delivery than in the non-delivery group. A positive association was noted between baPWV and smoking habit, and between SBP and BMI/smoking habit/alcohol consumption. In conclusions, menopause and delivery/delivery number promoted arteriosclerosis independently. Therefore, for these groups, long-term health management is required, and improvements in lifestyle need to be promoted.

Journal

  • Hirosaki Medical Journal

    Hirosaki Medical Journal 62 (1), 72-79, 2011

    Hirosaki University Graduate School of Medicine,Hirosaki Medical Society

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