Immunotoxicology assessment of vaccines and adjuvants in non-human primate model
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- YAMAMOTO Takuya
- Laboratory of Immunosenescence, National Institutes of Biomedical Innovation, Health and Nutrition
Bibliographic Information
- Other Title
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- 非ヒト霊長類モデルを用いたワクチン・アジュバントの免疫毒性研究
Abstract
<p>For development of next generation vaccines including COVID-19 vaccines, vaccine adjuvants targeting PRRs, which is related to the innate immune system, have shown great promise in their ability to enhance responses to component vaccines. However there is also a risk to induce massive unexpected inflammation by using these adjuvants. Thus it is important to carefully select the correct pre-clinical model to evaluate the safety and efficacy of the adjuvanted vaccines.</p><p>In this presentation, we will introduce our recent data regarding development of vaccines and adjuvants in non-human primate model and discuss about how we can use this model more efficiently for immunotoxicology assessment in future.</p>
Journal
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- Annual Meeting of the Japanese Society of Toxicology
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Annual Meeting of the Japanese Society of Toxicology 48.1 (0), S24-5-, 2021
The Japanese Society of Toxicology
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Details 詳細情報について
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- CRID
- 1390570486221110912
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- NII Article ID
- 130008073907
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed