Multivariate analysis reveals oral health-related quality of life of complete denture wearers with denture adhesives: a multicenter randomized controlled trial

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  • Ito Yoshihiko
    The Japan Denture Care Society, Japan Division of Aging and Geriatric Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan
  • Hong Guang
    The Japan Denture Care Society, Japan Division for Globalization Initiative, Liaison Center for Innovative Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan
  • Tsuboi Akito
    The Japan Denture Care Society, Japan Division of Community Oral Health Science, Department of Community Medical Supports, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
  • Kawai Yasuhiko
    The Japan Denture Care Society, Japan Department of Removable Prosthodontics, Nihon University School of Dentistry at Matsudo, Chiba, Japan
  • Kondo Hisatomo
    The Japan Denture Care Society, Japan Department of Prosthodontics and Oral Implantology, School of Dentistry, Iwate Medical University, Morioka, Japan
  • Nomura Taro
    The Japan Denture Care Society, Japan Department of Prosthodontics and Oral Implantology, School of Dentistry, Iwate Medical University, Morioka, Japan
  • Kimoto Suguru
    The Japan Denture Care Society, Japan Department of Removable Prosthodontics, Nihon University School of Dentistry at Matsudo, Chiba, Japan
  • Gunji Atsuko
    The Japan Denture Care Society, Japan Department of Removable Prosthodontics, Nihon University School of Dentistry at Matsudo, Chiba, Japan
  • Suzuki Asako
    The Japan Denture Care Society, Japan Department of Removable Prosthodontics, Nihon University Graduate School of Dentistry at Matsudo, Chiba, Japan
  • Ohwada Gaku
    The Japan Denture Care Society, Japan Gerodontology and Oral Rehabilitation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
  • Minakuchi Shunsuke
    The Japan Denture Care Society, Japan Gerodontology and Oral Rehabilitation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
  • Sato Yusuke
    The Japan Denture Care Society, Japan Gerodontology and Oral Rehabilitation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
  • Suzuki Tetsuya
    The Japan Denture Care Society, Japan Section of Oral Prosthetic Engineering, Tokyo Medical and Dental University, Tokyo, Japan
  • Kimoto Katsuhiko
    The Japan Denture Care Society, Japan Division of Prosthodontics & Oral Rehabilitation Department of Oral Function and Restoration Graduate School of Dentistry Kanagawa Dental University, Kanagawa, Japan
  • Hoshi Noriyuki
    The Japan Denture Care Society, Japan Division of Prosthodontics & Oral Rehabilitation Department of Oral Function and Restoration Graduate School of Dentistry Kanagawa Dental University, Kanagawa, Japan
  • Saita Makiko
    The Japan Denture Care Society, Japan Division of Prosthodontics & Oral Rehabilitation Department of Oral Function and Restoration Graduate School of Dentistry Kanagawa Dental University, Kanagawa, Japan
  • Yoneyama Yoshikazu
    The Japan Denture Care Society, Japan Department of Removable Prosthodontics, Tsurumi University School of Dental Medicine, Kanagawa, Japan
  • Sato Yohei
    The Japan Denture Care Society, Japan Department of Removable Prosthodontics, Tsurumi University School of Dental Medicine, Kanagawa, Japan
  • Morokuma Masakazu
    The Japan Denture Care Society, Japan Morokuma Dental Clinic, Nagasaki, Japan
  • Okazaki Joji
    The Japan Denture Care Society, Japan Department of Removable Prosthodontics and Occlusion Osaka Dental University, Osaka, Japan
  • Maeda Takeshi
    The Japan Denture Care Society, Japan Department of Removable Prosthodontics and Occlusion Osaka Dental University, Osaka, Japan
  • Nakai Kenichiro
    The Japan Denture Care Society, Japan Department of Removable Prosthodontics and Occlusion Osaka Dental University, Osaka, Japan
  • Ichikawa Tetsuo
    The Japan Denture Care Society, Japan Department of Prosthodontics and Oral Rehabilitation, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan
  • Nagao Kan
    The Japan Denture Care Society, Japan Department of Prosthodontics and Oral Rehabilitation, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan
  • Fujimoto Keiko
    The Japan Denture Care Society, Japan Department of Prosthodontics and Oral Rehabilitation, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan
  • Murata Hiroshi
    The Japan Denture Care Society, Japan Department of Prosthetic Dentistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
  • Kurogi Tadafumi
    The Japan Denture Care Society, Japan Department of Prosthetic Dentistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
  • Takase Kazuma
    The Japan Denture Care Society, Japan Department of Prosthetic Dentistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
  • Nishimura Masahiro
    The Japan Denture Care Society, Japan Department of Oral and Maxillofacial Prosthodontics, Field of Oral and Maxillofacial Rehabilitation, Course for Advanced Therapeutic, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
  • Nishi Yasuhiro
    The Japan Denture Care Society, Japan Department of Oral and Maxillofacial Prosthodontics, Field of Oral and Maxillofacial Rehabilitation, Course for Advanced Therapeutic, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
  • Murakami Mamoru
    The Japan Denture Care Society, Japan Denture Prosthodontic Restoration, Advanced Dentistry Center, Kagoshima University Medical and Dental Hospital, Kagoshima, Japan
  • Hosoi Toshio
    The Japan Denture Care Society, Japan Tsurumi University School of Dental Medicine, Kanagawa, Japan
  • Hamada Taizo
    The Japan Denture Care Society, Japan Hiroshima University, Hiroshima, Japan

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<p>Purpose To investigate the difference in improvement of oral health-related quality of life (OHR-QoL) depending on the oral and denture conditions of a complete denture wearer when using a cream or powder type denture adhesive in a 10-center parallel randomized clinical trial.</p><p>Methods Two hundred edentulous subjects who wore complete dentures were allocated to each of the three groups according to denture adhesive type: cream, powder, and control (saline solution). The materials were applied to the mucosal surface of the dentures for 4 days, and baseline data and data after the intervention were collected. OHR-QoL was assessed using the Japanese version of the modified Oral Health Impact Profile for Edentulous Patients (OHIP-EDENT-J) scale for outcome. Multivariate analysis was used to investigate improvements in OHR-QoL according to participant characteristics among complete denture wearers using these materials.</p><p>Results OHIP-EDENT-J scores were significantly decreased in all groups after the intervention (p < 0.05); however, there were no statistically significant differences among the groups. Multiple logistic regression analysis revealed a significant association between the vertical height of the maxillary and mandibular alveolar ridge and OHIP-EDENT-J scores in the cream-type denture adhesive group. In contrast, there were no significant association between participant characteristics and OHIP-EDENT-J scores in the powder-type adhesive and control groups.</p><p>Conclusions The use of denture adhesives could improve OHR-QoL for complete denture wearers. The cream-type denture adhesives may be expected to improve OHR-QoL in patients with poor residual ridge conditions compared with patients with good residual ridge conditions.</p>

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