A Case of Aspiration of High-molecular Polymer Sevelamer Hydrochloride That Caused Dyspnea
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- Ueda Masahide
- Department of Respiratory Medicine, Saiseikai Suita Hospital
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- Okada Asuka
- Department of Respiratory Medicine, Saiseikai Suita Hospital
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- Watabe Yuma
- Department of Respiratory Medicine, Saiseikai Suita Hospital
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- Koyama Katsumasa
- Department of Respiratory Medicine, Saiseikai Suita Hospital
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- Inui Yusuke
- Department of Respiratory Medicine, Saiseikai Suita Hospital
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- Furuyama Tatsuhiro
- Department of Respiratory Medicine, Saiseikai Suita Hospital
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- Ibaraki Takahiro
- Department of Respiratory Medicine, Saiseikai Suita Hospital
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- Mito Fumitaka
- Department of Respiratory Medicine, Saiseikai Suita Hospital
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- Takenaka Hideaki
- Department of Respiratory Medicine, Saiseikai Suita Hospital
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- Choh Sumito
- Department of Respiratory Medicine, Saiseikai Suita Hospital
Bibliographic Information
- Other Title
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- 高分子ポリマーであるセベラマー塩酸塩の誤嚥により呼吸困難を来した1例
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Abstract
<p>Background. The phosphate binder sevelamer hydrochloride is a high-molecular-weight polymer. It becomes gelatinous and expands eight-fold in aqueous solutions. Sevelamer crystals deposited on the mucosa can lead to mucosal injury. Case. A 67-year-old man with chronic renal disease had received maintenance hemodialysis for about 4 years. In early June of X, he choked on a tablet of sevelamer hydrochloride (Phosblock®) before breakfast. He felt continuous discomfort in his pharynx and mild dyspnea. His respiratory symptoms worsened during hemodialysis that afternoon. Chest computed tomography showed stenosis of the left basal bronchus and atelectasis of the left S8. Bronchoscopy showed edematous mucosa from the left lower lobe bronchus to the basal bronchus and gel-like white foreign bodies adhering to the basal bronchus, thought to be bronchial foreign bodies of sevelamer hydrochloride. We removed the bodies as much as possible using biopsy forceps and a brush. Conclusion. Sevelamer hydrochloride has a property of expanding on water absorption. Therefore, sevelamer aspiration is likely to cause airway obstruction. It is also necessary to be aware of the risk of mucosal injury due to sevelamer crystals.</p>
Journal
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- The Journal of the Japan Society for Respiratory Endoscopy
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The Journal of the Japan Society for Respiratory Endoscopy 43 (5), 510-514, 2021-09-25
The Japan Society for Respiratory Endoscopy
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Keywords
Details 詳細情報について
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- CRID
- 1390571240017224576
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- NII Article ID
- 130008105761
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- ISSN
- 21860149
- 02872137
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed