The Estimated Prevalence and Incidence of Endometriosis With the Korean National Health Insurance Service-National Sample Cohort (NHIS-NSC): A National Population-Based Study
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- Kim Hyunkyung
- Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea
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- Lee Minkyoung
- Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea
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- Hwang Hyejin
- Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea
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- Chung Youn-Jee
- Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea
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- Cho Hyun-Hee
- Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea
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- Yoon Hyonjee
- Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea
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- Kim Mira
- Department of Preventive Medicine, College of Medicine, The Catholic University of Korea
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- Chae Kyung-Hee
- Department of Preventive Medicine, College of Medicine, The Catholic University of Korea
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- Jung Chai Young
- Biomedical Research Institute, Inha University Hospital
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- Kim Sukil
- Department of Preventive Medicine, College of Medicine, The Catholic University of Korea
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- Kim Mee-Ran
- Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea
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<p>Background: The incidence and prevalence of endometriosis remain unclear due to diagnostic difficulties. Especially, there has been little information regarding the population-based epidemiology of endometriosis. The purpose of this study is to estimate the prevalence and incidence of endometriosis in Korea based on the health insurance claims data.</p><p>Methods: This study is a retrospective cohort study using the Korean National Health Insurance Service-National Sample Cohort, which correspond to approximately 1 million Korean populations from 2002 to 2013. Patients aged 15–54 years were selected, and the prevalence and incidence of endometriosis were estimated by time and age groups.</p><p>Results: The age-adjusted prevalence rate of endometriosis also increased from 2.12 per 1,000 persons (95% confidence interval [CI], 2.01–2.24) in 2002 to 3.56 per 1,000 persons (95% CI, 3.40–3.71) in 2013. The average adjusted incidence showed no statistically significant increase. However, the age-specific incidence of the 15–19 and 20–24 years age groups increased significantly from 0.24 and 1.29 per 1,000 persons in 2003 to 2.73 and 2.71 per 1,000 persons in 2013 (R2 = 0.93 and 0.77, P < 0.001), while the incidence rate of the age group 40–44 and 45–49 years decreased from 2.36 and 1.72 per 1,000 persons in 2003 to 0.81 and 0.27 per 1,000 persons in 2013 (R2 = 0.83 and 0.89, P < 0.001).</p><p>Conclusion: The prevalence and incidence of endometriosis in Korean women were lower than that of previous reports in high-risk population studies. Furthermore, we found a significant increase in the diagnosis of endometriosis in younger age groups.</p>
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ｅｐｉｄｅｍｉｏｌｏｇｙ
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Ｊｏｕｒｎａｌ ｏｆ Ｅｐｉｄｅｍｉｏｌｏｇｙ 31 (12), 593-600, 2021-12-05
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