A Case of Thyroid-like Low Grade Nasopharyngeal Papillary Adenocarcinoma of the Posterior Nasal Septum

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  • Oguchi Arisa
    Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University
  • Kumai Takumi
    Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University
  • Kishibe Kan
    Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University
  • Takahara Miki
    Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University
  • Katada Akihiro
    Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University
  • Hayashi Tatsuya
    Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University
  • Harabuchi Yasuaki
    Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University

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  • 鼻中隔後端に発生したThyroid-like low grade nasopharyngeal papillary adenocarcinoma例

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<p>Thyroid-like low grade nasopharyngeal papillary adenocarcinoma (TL-LGNPPA) is a rare malignant tumor that originates in the nasopharynx. Pathologically, the tumor shows papillary thyroid cancer-like findings of a thyroid transcription factor-1 (TTF-1)-positive and thyroglobulin (TG)-negative status. We report a case of nasopharyngeal papillary adenocarcinoma at the posterior end of the nasal septum.</p><p>A 50-year-old woman presented with sore throat in our department. Nasal endoscopy revealed a pedunculated tumor at the posterior end of the nasal septum. CT and MRI showed a pedunculated tumor without cervical lymph node swelling. Biopsy revealed a TL-LGNPPA that was TTF-1-positive and TG-negative. The tumor was endoscopically resected under general anesthesia without any complications. The pathological margin was negative. No recurrence or metastasis has been observed in one year and 6 months after the operation.</p>

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