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Histological Distribution of MHC Class II‒expressing Cells Responsible for Ingestion of Blood‒borne Exogenous Particles in Japanese Flounder <i>Paralichthys olivaceus</i>
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- Kurata Osamu
- Laboratory of Aquatic Medicine, School of Veterinary Medicine, Nippon Veterinary and Life Science University
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- Miyashita Suyu
- Laboratory of Aquatic Medicine, School of Veterinary Medicine, Nippon Veterinary and Life Science University
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- Wada Shinpei
- Laboratory of Aquatic Medicine, School of Veterinary Medicine, Nippon Veterinary and Life Science University
Bibliographic Information
- Other Title
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- 血液中の異物を捕食するヒラメMHCクラスII発現細胞の組織分布
- Histological Distribution of MHC Class Ⅱ : expressing Cells Responsible for Ingestion of Blood-borne Exogenous Particles in Japanese Flounder Paralichthys olivaceus
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Description
<p>This study investigated the ability of MHC class II‒expressing cells to ingest blood-borne exogenous particles and their tissue distribution in Japanese flounder Paralichthys olivaceus. Carbon particles were injected into a blood vessel in the caudal peduncle. After 3 h, carbon-laden MHC class II‒expressing cells were found in the spleen and the kidney, and localised in ellipsoids, splenic cords, peritubular sinuses and interstitial veins of the kidney. Additionally, the percentage of these cells was significantly higher in the spleen than the kidney. These results suggest that the spleen is the main organ that plays a role in the ingestion of blood‒borne exogenous particles for antigen presentation.</p>
Journal
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- Fish Pathology
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Fish Pathology 56 (4), 216-219, 2021-12-15
The Japanese Society of Fish Pathology
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Details 詳細情報について
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- CRID
- 1390572012409168896
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- NII Article ID
- 130008134326
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- NII Book ID
- AN00063165
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- ISSN
- 18817335
- 0388788X
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- NDL BIB ID
- 031893897
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- IRDB
- NDL Search
- Crossref
- CiNii Articles
- KAKEN
- OpenAIRE
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- Abstract License Flag
- Disallowed