Effectiveness of Centrifuge-induced Artificial Gravity with Ergometric Exercise as a Countermeasure during Simulated Microgravity Exposure in Humans

DOI IR IR (HANDLE) Open Access

Search this article

Description

To test the effectiveness of centrifuge-induced artificial gravity with ergometric exercise, 12 healthy young men (20.7±1.9yrs) were exposed to simulated microgravity for 14 days of-6°head-down bedrest. Half the subjects were randomly selected and loaded 1.2 G artificial gravity with 60 W (four out of six subjects) or 40 W (two out of six subjects) of ergometric workload on days 1,2,3,5,7,9,11.12,13,14(CM group). The rest of the subjects served as the control. Anti-G score, defined as the G-load x running time to the endpoint, was significantly elongated by the load of the centrifuge-ergometer.Plasma volume loss was suppressed(-5.0±2.4 vs-16.4±1.9%),and fluid volume shift was prevented by the countermeasure load. Elevated heart rate and muscle sympathetic nerve activity after bedrest were counteracted, and exaggerated response to head-up tilt was also suppressed. Centrifuge-induced artificial gravity with exercise is effective in preventing cardiovascular deconditioning due to microgravity exposure, however, as effective and appropriate regimen (magnitude of G-load and exercise workload)should be determined in future studies.

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top