自己免疫疾患非合併胸腺MALTリンパ腫の1例

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Other Title
  • ショウレイ ジコ メンエキ シッカン ヒガッペイ キョウセン MALT リンパシュ ノ 1レイ
  • Thymic Mucosa-associated Lymphoid Tissue Lymphoma Not Associated with Autoimmune Disease. A Case Report and Literature Review

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Abstract

type:TOHO University Scholarly Publication

症例

50歳代女性.大腸癌術後観察中,前上縦隔の腫瘤を指摘され胸腔鏡下摘出術が施行された.嚢胞を伴う境界明瞭な結節性病変で単球様B細胞の増生とリンパ上皮性病変からMALTリンパ腫と診断した.胸腺MALTリンパ腫は自己免疫疾患を高率に合併するが,本例は非合併例であった.自己免疫疾患合併の有無によるMALTリンパ腫としての臨床病理学的差異について文献的に検討したが,明確な違いは見いだせなかった.A 50-year-old woman, who was being monitored following surgery for colon cancer, underwent thoracoscopic surgery to resect an anterior mediastinal tumor. The tumor was a well-defined nodular lesion accompanied by cysts, with infiltration of monocytoid B cells, and was a lymphoepithelial lesion. Therefore, we diagnosed it as a mucosa-associated lymphoid tissue (MALT) lymphoma. Most thymic MALT lymphomas are manifested along with autoimmune disease. However, in this case no autoimmune disease was observed. We reviewed the literature and found that there were no obvious clinicopathological differences between cases with MALT lymphoma with and without autoimmune disease.

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