Endovascular Treatment for Lower-extremity Arterial Thrombosis in a Patient with Congenital Afibrinogenemia and a History of Bleeding Complications

  • Hiramatsu Daisuke
    Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan
  • Ogihara Yoshito
    Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan
  • Matsumoto Takeshi
    Department of Transfusion Medicine and Cell Therapy, Mie University Hospital, Japan
  • Sato Kei
    Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan
  • Takasaki Akihiro
    Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan
  • Kurita Tairo
    Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan
  • Okamoto Ryuji
    Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan
  • Wada Hideo
    Department of General and Laboratory Medicine, Mie Prefectural General Medical Center, Japan; Associated Department with Mie Graduate School of Medicine, Japan
  • Dohi Kaoru
    Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan

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Description

<p>Congenital afibrinogenemia is a rare autosomal recessive blood disorder that accompanies thrombotic complications and is associated with bleeding tendency. The management of these opposing complications remains a challenge. Endovascular treatment (EVT) for peripheral arterial thrombosis has not been described in previous studies. A 57-year-old man with congenital afibrinogenemia developed back pain and left lower leg pain. The cause of the pain was confirmed to be renal infarction and lower extremity arterial thrombosis by Doppler ultrasound and contrast-enhanced computed tomography. He was treated with EVT for the lower extremity arterial thrombosis, leading to an excellent short-term improvement without bleeding. </p>

Journal

  • Internal Medicine

    Internal Medicine 61 (3), 361-364, 2022-02-01

    The Japanese Society of Internal Medicine

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