Investigation of Shampoo Moisturizing Effect Using Repeated Open Testing

NOMA Atsushi, MIYATA Atsushi, MOMOTA Yutaka

doi:10.11252/dobutsurinshoigaku.30.6

<p>Availability of repeated open testing in dogs was evaluated using seven healthy dogs. The skin damage by different shampoos was assessed by measuring the skin barrier function, including transepidermal water loss (TEWL) and skin hydration. We prepared four different shampoo products to perform repeated open testing. The shampoo product with sodium laureth sulfate (SLS) was used as the positive control, and rinsing without a shampoo product used as the negative control. As skin damage by surfactants is influenced by their molecular weights, a shampoo product containing polyglyceryl-10 laurate, a high molecular surfactant, was compared with a shampoo product containing a low molecular surfactant, SLS. Skin damage due to shampooing can be suppressed by adding a moisturizer to the shampoo products; hence, a shampoo product containing polyquaternium-10, a widely-used moisturizer, was also used. TEWL was significantly increased in the SLS shampoo group than in the rinsing group. The moisturizer and polyglyceryl-10 laurate shampoo products significantly suppressed the increase in TEWL compared with the SLS shampoo product. Skin hydration values were not significantly different among the four shampoo product groups. The present study demonstrated the availability of repeated open testing in dogs, with SLS shampoo product serving as the positive control. In addition, polyglyceryl-10 laurate and polyquaternium-10 were also shown to suppress the skin damage by shampooing in dogs. To the best of our knowledge, this is the first study verifying the applicability of repeated open testing in dogs.</p>

Investigation of Shampoo Moisturizing Effect Using Repeated Open Testing

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